Some of my issues I attribute to my car accident– they wanted to rule out MS. I have to say I had a doctor tell me that an MRI is the definitive say on MS. However, reading up on the subject I think that doctor was full of it. I read that the plaques indicative of MS sometimes don't show up on MRI's until ten years later. Other things they can do to test for demyelination are EEG's (which your sister will probably have) and for MS is a lumbar puncture–which ironically my aunt had and her doctor told *her* that was the definitive yes or no. You just have to keep at it to rule everything out.

My sister had an MRI on her back the other day because of injuries due to car accidents (yes, more than one) and back surgery in the past.  Apparently, there is evidence of myelinization so now they think she might have the beginnings of MS.  How do they reach the actual diagnosis for MS, anyone know?